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Short term outcomes of neonatal opioid withdrawal syndrome: a comparison of two approaches
Journal of Perinatology ( IF 2.9 ) Pub Date : 2024-04-02 , DOI: 10.1038/s41372-024-01953-z
Rachana Singh , Patrice Melvin , Elisha M. Wachman , Robert Rothstein , Davida M. Schiff , Jennifer Murzycki , Marcia VanVleet , Munish Gupta , Jonathan M. Davis ,

Objective

To evaluate outcomes in opioid exposed neonates (OENs) assessed by the Eat, Sleep, Console (ESC) tool compared to the Finnegan Neonatal Abstinence Scoring System (FNASS).

Methods

Retrospective analysis of a statewide database of OENs from 2017 to 2020 with birthing hospitals classified based on the assessment tool used. Four main outcomes were examined using multivariable and Poisson logistic regression models.

Results

Of 2375 OENs, 42.1% received pharmacotherapy (PT) with a consistent decrease in PT, length of treatment (LOT), and length of stay (LOS) over the study period. There was no change in use of mother’s own milk (MoM). While outcomes were significantly associated with several specific variables, there were no differences in outcomes between assessment methods.

Conclusion

While there was a significant decrease over time in PT, LOT, and LOS, improvements were independent of the assessment tool used and likely related to the increased use of non-pharmacologic care.



中文翻译:

新生儿阿片类药物戒断综合征的短期结果:两种方法的比较

客观的

与芬尼根新生儿戒断评分系统 (FNASS) 相比,通过饮食、睡眠、控制台 (ESC) 工具评估阿片类药物暴露新生儿 (OEN) 的结果。

方法

对 2017 年至 2020 年全州 OEN 数据库进行回顾性分析,并根据所使用的评估工具对分娩医院进行分类。使用多变量和泊松逻辑回归模型检查了四个主要结果。

结果

在 2375 名 OEN 中,42.1% 接受了药物治疗 (PT),并且在研究期间 PT、治疗时间 (LOT) 和住院时间 (LOS) 持续下降。母乳的使用(MoM)没有变化。虽然结果与几个特定变量显着相关,但评估方法之间的结果没有差异。

结论

虽然 PT、LOT 和 LOS 随着时间的推移显着下降,但改善与所使用的评估工具无关,并且可能与非药物护理的使用增加有关。

更新日期:2024-04-02
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