For liver volumetry, manual tracing on computed tomography (CT) images is time-consuming and operator dependent. To overcome these disadvantages, several three-dimensional simulation software programs have been developed; however, their efficacy has not fully been evaluated. Three physicians performed liver volumetry on preoperative CT images on 30 patients who underwent formal right hepatectomy, using manual tracing volumetry and two simulation software programs, SYNAPSE and syngo.via. The future liver remnant (FLR) was calculated using each method of volumetry. The primary endpoint was reproducibility and secondary outcomes were calculation time and learning curve. The mean FLR was significantly lower for manual volumetry than for SYNAPSE or syngo.via; there was no significant difference in mean FLR between the two software-based methods. Reproducibility was lower for the manual method than for the software-based methods. Mean calculation time was shortest for SYNAPSE. For the two physicians unfamiliar with the software, no obvious learning curve was observed for using SYNAPSE, whereas learning curves were observed for using syngo.via. Liver volumetry was more reproducible and faster with three-dimensional simulation software, especially SYNAPSE software, than with the conventional manual tracing method. Software can help even inexperienced physicians learn quickly how to perform liver volumetry.

中文翻译：

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使用手动方法和肝脏分析软件进行肝脏容量测定的重现性和效率

对于肝脏体积测定，计算机断层扫描 (CT) 图像的手动追踪非常耗时且依赖于操作员。为了克服这些缺点，已经开发了几种三维模拟软件程序；然而，它们的功效尚未得到充分评估。三名医生使用手动追踪体积测定法和两个模拟软件程序 SYNAPSE 和 syngo.via，对 30 名接受正式右肝切除术的患者的术前 CT 图像进行了肝脏体积测定。使用每种容量法计算未来的肝脏残余物（FLR）。主要终点是可重复性，次要终点是计算时间和学习曲线。手动容量法的平均 FLR 显着低于 SYNAPSE 或 syngo.via；两种基于软件的方法之间的平均 FLR 没有显着差异。手动方法的重现性低于基于软件的方法。 SYNAPSE 的平均计算时间最短。对于不熟悉该软件的两位医生，使用 SYNAPSE 没有观察到明显的学习曲线，而使用 syngo.via 则观察到学习曲线。与传统的手动追踪方法相比，使用三维模拟软件（尤其是 SYNAPSE 软件）进行肝脏体积测定具有更高的可重复性和更快的速度。软件甚至可以帮助没有经验的医生快速学习如何进行肝脏容量测定。