The study demonstrates three-dimensional depth-resolved Optical Coherence Tomography Angiography (OCTA) and Doppler OCT imaging performed on the anterior segment of the human eye. A high-speed swept-source OCT system was developed utilizing a swept-source laser having a 100 kHz A-scan sweep rate and centre wavelength at 1060 nm. The proposed system has an axial resolution of 4.5 µm and a transverse imaging resolution of 14 µm. The Doppler OCT provides information regarding the direction of blood flow in corneoscleral junction vessels, which employs the Joint Spectral and Time domain OCT (STdOCT) method. Parameters influencing the imaging of various vessels, like scanning density, A-scan rate, B-scan averaging, and number of BM scanning repeats, were also studied. Slit lamp images and OCT angiography en-face projections produced from PVOCTA (Phase-variance OCTA) and STdOCTA from the same regular patients were compared in order to demonstrate the additional potential of the system. The vascular systems at the Limbus consisting of circulatory, lymphatic, and aqueous outflow systems were imaged and presented. The output clinical parameters of the system will contribute to understanding the blood circulation with directionality at the limbus location, which can be further utilized to identify glaucoma. In the author's opinion, this article represents the first attempt to provide Doppler OCTA data for the anterior chamber of the human eye.

中文翻译：

---

使用 100 KHz A 扫描速率扫频光学相干断层扫描/血管造影 (OCT/A) 系统对人体角巩膜交界处 (Limbus) 脉管系统进行成像

该研究展示了对人眼眼前节进行的三维深度分辨光学相干断层扫描血管造影 (OCTA) 和多普勒 OCT 成像。利用具有 100 kHz A 扫描扫描速率和 1060 nm 中心波长的扫频源激光器开发了高速扫频源 OCT 系统。该系统的轴向分辨率为 4.5 µm，横向成像分辨率为 14 µm。多普勒 OCT 提供有关角巩膜连接血管中血流方向的信息，该方法采用联合频谱和时域 OCT (STdOCT) 方法。还研究了影响各种血管成像的参数，如扫描密度、A 扫描速率、B 扫描平均和 BM 扫描重复次数。对来自相同常规患者的裂隙灯图像和 PVOCTA（相位方差 OCTA）和 STdOCTA 产生的 OCT 血管造影正面投影进行比较，以证明该系统的额外潜力。对由循环、淋巴和房水流出系统组成的角膜缘的血管系统进行了成像和呈现。系统输出的临床参数将有助于了解角膜缘位置的血液循环的方向性，这可以进一步用于识别青光眼。作者认为，本文代表了为人眼前房提供多普勒 OCTA 数据的首次尝试。