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MajorK: Majority Based kmer Matching in Commodity DRAM
IEEE Computer Architecture Letters ( IF 2.3 ) Pub Date : 2024-04-02 , DOI: 10.1109/lca.2024.3384259
Z. Jahshan 1 , L. Yavits 1
Affiliation  

Fast parallel search capabilities on large datasets are required across multiple application domains. One such domain is genome analysis, which requires high-performance k mer matching in large genome databases. Recently proposed solutions implemented k mer matching in DRAM, utilizing its sheer capacity and parallelism. However, their operation is essentially bit-serial, which ultimately limits the performance, especially when matching long strings, as customary in genome analysis pipelines. The proposed solution, MajorK, enables bit-parallel majority based k mer matching in an unmodified commodity DRAM. MajorK employs multiple DRAM row activation, where the search patterns (query k mers) are coded into DRAM addresses. We evaluate MajorK on viral genome k mer matching and show that it can achieve up to 2.7 $ \times $ higher performance while providing a better matching accuracy compared to state-of-the-art DRAM based k mer matching accelerators.

中文翻译:

MajorK:商品 DRAM 中基于多数的 kmer 匹配

跨多个应用程序域需要对大型数据集的快速并行搜索功能。基因组分析就是这样的领域之一,它需要 在大型基因组数据库中进行高性能的k mer 匹配。最近提出的解决方案 利用其巨大的容量和并行性在 DRAM 中实现了 kmer 匹配然而,它们的操作本质上是位串行的,这最终限制了性能,特别是在匹配长字符串时,正如基因组分析管道中的惯例。所提出的解决方案 MajorK 可 在未修改的商品 DRAM 中实现基于位并行多数的k mer 匹配。 MajorK 采用多 DRAM 行激活,其中搜索模式(查询k 聚体)被编码到 DRAM 地址中。我们在病毒基因组k mer 匹配上评估 MajorK ,结果表明它可以达到 2.7 $\次$与最先进的基于 DRAM 的k mer 匹配加速器相比,它具有更高的性能,同时提供更好的匹配精度。
更新日期:2024-04-02
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