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Ivacaftor attenuates gentamicin-induced ototoxicity through the CFTR-Nrf2-HO1/NQO1 pathway
Redox Report ( IF 3.8 ) Pub Date : 2024-04-02 , DOI: 10.1080/13510002.2024.2332038
Rui Hu 1, 2 , Fan Wu 2, 3, 4 , Yi-Qing Zheng 1, 2, 3
Affiliation  

Gentamicin is one of the most common ototoxic drugs that can lower patients' quality of life. Oxidative stress is a key factors inducing sensory hair cell death during gentamicin administration. So...

中文翻译:

Ivacaftor 通过 CFTR-Nrf2-HO1/NQO1 途径减轻庆大霉素诱导的耳毒性

庆大霉素是最常见的耳毒性药物之一,会降低患者的生活质量。氧化应激是庆大霉素给药期间诱导感觉毛细胞死亡的关键因素。所以...
更新日期:2024-04-03
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