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Dietary Supplementation with Nervonic Acid Ameliorates Cerebral Ischemia-Reperfusion Injury by Modulating of Gut Microbiota Composition-Fecal Metabolites Interaction
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2024-04-02 , DOI: 10.1002/mnfr.202300671
Hui Zhou 1 , Ziyi Chen 2 , Jingbin Li 1 , Rongjin Wang 2 , Hongshi Bu 3 , Chengjiang Ruan 1
Affiliation  

Cerebral ischemia-reperfusion (IR) injury stands as a prominent global contributor to disability and mortality. Nervonic acid (NA), a bioactive elongated monounsaturated fatty acid, holds pivotal significance in human physiological well-being. This research aims to explore the prophylactic effects and fundamental mechanisms of NA in a rat model of cerebral IR injury.

中文翻译:

膳食补充剂神经酸通过调节肠道微生物群组成与粪便代谢物相互作用来改善脑缺血再灌注损伤

脑缺血再灌注(IR)损伤是全球致残和死亡的主要原因。神经酸(NA)是一种具有生物活性的长链单不饱和脂肪酸,在人类生理健康中具有至关重要的意义。本研究旨在探讨NA对大鼠脑IR损伤模型的预防作用及其基本机制。
更新日期:2024-04-02
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