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Influence of sample orientation on cytocompatibility of pure magnesium
Materials Chemistry and Physics ( IF 4.6 ) Pub Date : 2024-03-26 , DOI: 10.1016/j.matchemphys.2024.129247
Mojtaba Fatehi Mollayousef , Mehdi Malekan , Ahmad Bahmani , Mehrab Lotfpour

This study aimed to investigate how sample orientation and texture distributions affect pure magnesium (Mg) cytocompatibility behavior and discuss the connection between metallurgical and microstructural factors with cytocompatibility. Three samples with varying orientations but the same grain size were used to investigate the influence of texture distribution on cell viability and adhesion. Results showed that an increase in the intensity of hexagonal closed-packed (hcp) basal planes or texture distribution with more basal planes improved cell viability and adhesion. Corrosion behavior and surface energy were identified as the link between microstructural factors and cytocompatibility properties. Different corrosion tests were performed to observe the enhancement of corrosion resistance whenever the texture distribution was dominated with basal planes. These findings suggest that the cytocompatibility of Mg alloys is fundamentally related to the orientation or texture distribution of the samples, with more hcp basal planes resulting in better cell viability and adhesion.

中文翻译:

样品方向对纯镁细胞相容性的影响

本研究旨在研究样品方向和纹理分布如何影响纯镁 (Mg) 细胞相容性行为,并讨论冶金和微观结构因素与细胞相容性之间的联系。使用具有不同方向但相同晶粒尺寸的三个样品来研究纹理分布对细胞活力和粘附的影响。结果表明,六边形密堆积 (hcp) 基面强度的增加或具有更多基面的纹理分布可改善细胞活力和粘附。腐蚀行为和表面能被认为是微观结构因素和细胞相容性之间的联系。当织构分布以基面为主时,进行不同的腐蚀测试来观察耐腐蚀性的增强。这些发现表明,镁合金的细胞相容性从根本上与样品的取向或纹理分布有关,更多的 hcp 基底平面导致更好的细胞活力和粘附。
更新日期:2024-03-26
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