Although researches on nanoparticle-based (NP-based) drug delivery system for atherosclerosis treatment have grown rapidly in recent years, there are limited studies in quantifying the effects of targeting drugs on plaque components and microenvironment. The purpose of the present study was to quantitatively assess the targeting therapeutic effects against atherosclerosis by establishing a multiscale mathematical model.

中文翻译：

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基于纳米颗粒的动脉粥样硬化靶向治疗的多尺度建模研究

尽管近年来用于治疗动脉粥样硬化的纳米颗粒（NP-based）药物递送系统的研究迅速发展，但量化靶向药物对斑块成分和微环境影响的研究有限。本研究的目的是通过建立多尺度数学模型来定量评估针对动脉粥样硬化的靶向治疗效果。