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Revolutionizing Wound Healing: Unleashing Nanostructured Lipid Carriers Embodied with Herbal Medicinal Plant
Current Pharmaceutical Biotechnology ( IF 2.8 ) Pub Date : 2024-04-03 , DOI: 10.2174/0113892010287720240322060706
Aditya Jain 1 , Shikha Yadav 1 , Javed Khan 1
Affiliation  

: Wound healing is crucial for maintaining skin integrity and preventing complications from external threats. Various plants, such as Achillea millefolium, Aloe vera, Curcuma longa, Calendula officinalis, Camellia sinensis, Azadirachta indica, and Plantago, have demonstrated wound healing capabilities and have been used in herbal medicine for wound care. NLCs are second-generation lipid nanoparticles, blending solid and liquid lipids to improve medication loading and limit leakage. NLCs have been used in various applications, including cosmeceuticals, chemotherapy, gene therapy, and brain targeting. Wound healing is divided into four stages: hemostasis, inflammatory response, proliferation, and remodeling. Factors such as age, gender, chronic disorders, and local agents like infections can affect recovery. These plants' antiinflammatory, antioxidant, and antibacterial activities have demonstrated potential in wound healing. Combining herbal medicinal plants and nanostructured lipid carriers (NLCs) can revolutionise wound treatment and improve overall healthcare outcomes.

中文翻译:

彻底改变伤口愈合:释放以草药为载体的纳米结构脂质载体

:伤口愈合对于维持皮肤完整性和防止外部威胁引起的并发症至关重要。各种植物,如蓍草、芦荟、姜黄、金盏花、茶花、印楝和车前草,已显示出伤口愈合能力,并已被用于伤口护理的草药中。 NLC 是第二代脂质纳米粒子,混合固体和液体脂质以改善药物负载并限制泄漏。 NLC 已用于多种应用,包括药妆品、化疗、基因治疗和脑靶向。伤口愈合分为四个阶段:止血、炎症反应、增殖和重塑。年龄、性别、慢性疾病和感染等局部因素都会影响康复。这些植物的抗炎、抗氧化和抗菌活性已显示出在伤口愈合方面的潜力。将草药植物与纳米结构脂质载体 (NLC) 相结合可以彻底改变伤口治疗并改善整体医疗保健结果。
更新日期:2024-04-03
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