Propargylic alcohols are regarded as a class of readily available and versatile synthons in organic synthesis. Due to their unique bifunctional character, the transformation of propargylic alcohols has been widely utilized as a powerful strategy for the construction of various functionalized frameworks over the past few decades. Recently, the radical transformation of propargylic alcohols has attracted considerable attention in synthetic chemistry. This review summarises recent progress in the radical transformation of propargylic alcohols. Based on the different mechanisms of radical formation underlying these transformations, this review has been divided into four parts: (1) transition‐metal catalyzed radical transformation; (2) photo‐induced radical transformation; (3) electroc‐induced radical transformation; and (4) metal‐free or oxidant‐mediated radical transformation of propargylic alcohols.

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炔丙醇自由基转化的最新进展

丙炔醇被认为是有机合成中一类容易获得且用途广泛的合成子。由于其独特的双功能特性，在过去的几十年里，炔丙醇的转化已被广泛用作构建各种功能化框架的有力策略。近年来，炔丙醇的自由基转化引起了合成化学领域的广泛关注。这篇综述总结了炔丙醇彻底转变的最新进展。基于这些转变背后自由基形成的不同机制，本文分为四个部分：（1）过渡金属催化的自由基转变； (2)光诱导自由基转变； (3)电诱导自由基转变； (4)炔丙醇的无金属或氧化剂介导的自由基转化。