This work investigates the husbandry microenvironment and health status of experimental mice to help create a suitable husbandry microenvironment for experimental animals, with the aim of ensuring the quality and animal welfare of experimental mice through a suitable husbandry microenvironment. Experimental measurements and computational fluid dynamics (CFD) are used to analyze the husbandry microenvironment of experimental mice, and indicators for judging the health status and husbandry microenvironments of experimental mice are proposed. The results show that the correlation between the health state of mice and abdominal heat flux reaches 0.786 (p = 0.01), and there is a significant difference between the environmental evaluation indexes of healthy and sick mice. The relationship between the mice and the husbandry microenvironments could be characterized by the C number, i.e.，C number is defined as the biological surface convective heat transfer number of the microenvironment, and the value of C number of the healthy mice could be referred to as about 0.3334. This is of guiding significance for the judgment of the health of experimental animals and the creation of a suitable husbandry microenvironment for experimental animals.

中文翻译：

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个体通风笼（IVC）实验小鼠饲养微环境及动物健康研究

本工作通过调查实验小鼠的饲养微环境和健康状况，帮助为实验动物创造合适的饲养微环境，旨在通过合适的饲养微环境保证实验小鼠的质量和动物福利。利用实验测量和计算流体力学（CFD）对实验小鼠的饲养微环境进行分析，提出判断实验小鼠健康状况和饲养微环境的指标。结果表明，小鼠健康状态与腹部热通量的相关性达到0.786（p = 0.01），健康与患病小鼠的环境评价指标存在显着差异。小鼠与饲养微环境的关系可用C数来表征，即C数定义为微环境的生物表面对流换热数，健康小鼠的C数值可表示为约0.3334。这对于判断实验动物的健康状况以及为实验动物创造适宜的饲养微环境具有指导意义。