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Etanercept-synthesizing adipose-derived stem cell secretome: A promising therapeutic option for inflammatory bowel disease.
World Journal of Gastrointestinal Surgery ( IF 2 ) Pub Date : 2024-4-5 , DOI: 10.4240/wjgs.v16.i3.882 Say-June Kim , Ok-Hee Kim , Ha-Eun Hong , Ji Hyeon Ju , Do Sang Lee
World Journal of Gastrointestinal Surgery ( IF 2 ) Pub Date : 2024-4-5 , DOI: 10.4240/wjgs.v16.i3.882 Say-June Kim , Ok-Hee Kim , Ha-Eun Hong , Ji Hyeon Ju , Do Sang Lee
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract, with tumor necrosis factor (TNF)-α playing a key role in its pathogenesis. Etanercept, a decoy receptor for TNF, is used to treat inflammatory conditions. The secretome derived from adipose-derived stem cells (ASCs) has anti-inflammatory effects, making it a promising therapeutic option for IBD.
中文翻译:
依那西普合成脂肪干细胞分泌组:炎症性肠病的一种有前途的治疗选择。
炎症性肠病(IBD)是一种胃肠道慢性炎症性疾病,肿瘤坏死因子(TNF)-α在其发病机制中发挥着关键作用。依那西普是 TNF 的诱饵受体,用于治疗炎症。源自脂肪干细胞 (ASC) 的分泌蛋白组具有抗炎作用,使其成为 IBD 有前景的治疗选择。
更新日期:2024-04-05
中文翻译:
依那西普合成脂肪干细胞分泌组:炎症性肠病的一种有前途的治疗选择。
炎症性肠病(IBD)是一种胃肠道慢性炎症性疾病,肿瘤坏死因子(TNF)-α在其发病机制中发挥着关键作用。依那西普是 TNF 的诱饵受体,用于治疗炎症。源自脂肪干细胞 (ASC) 的分泌蛋白组具有抗炎作用,使其成为 IBD 有前景的治疗选择。