IntroductionPhysical activity influences psychological well-being. This study aimed to determine the impact of exercise intensity on psychological well-being and alterations in emotion-related brain functional connectivity (FC).MethodsTwenty young, healthy, trained athletes performed a low- and high-intensity interval exercise (LIIE and HIIE) as well as a control condition in a within-subject crossover design. Before and after each condition, Positive And Negative Affect Scale (PANAS) was assessed as well as resting-state functional MRI (rs-fMRI). Voxel-wise FC was examined for bilateral amygdala seed region to whole-brain and emotion-related anatomical regions (e.g., insula, temporal pole, precuneus). Data analyses were performed using linear mixed-effect models with fixed factors condition and time.ResultsThe PANAS Positive Affect scale showed a significant increase after LIIE and HIIE and a significant reduction in Negative Affect after the control condition. In rs-fMRI, no significant condition-by-time interactions were observed between the amygdala and whole brain. Amygdala-precuneus FC analysis showed an interaction effect, suggesting reduced post-exercise anticorrelation after the control condition, but stable, or even slightly enhanced anticorrelation for the exercise conditions, especially HIIE.DiscussionIn conclusion, both LIIE and HIIE had positive effects on mood and concomitant effects on amygdala-precuneus FC, particularly after HIIE. Although no significant correlations were found between amygdala-precuneus FC and PANAS, results should be discussed in the context of affective disorders in whom abnormal amygdala-precuneus FC has been observed.

中文翻译：

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不同强度的急性体力消耗后杏仁核和楔前叶之间静息态功能连接的差异调节：情感调节作用的迹象

简介身体活动影响心理健康。本研究旨在确定运动强度对心理健康以及情绪相关大脑功能连接 (FC) 变化的影响。方法 20 名年轻、健康、训练有素的运动员进行了低强度和高强度间歇运动（LIIE 和 HIIE）以及受试者内交叉设计中的控制条件。在每种情况之前和之后，评估积极和消极影响量表（PANAS）以及静息态功能磁共振成像（rs-fMRI）。检查体素 FC 的双侧杏仁核种子区域到全脑和情绪相关的解剖区域（例如岛叶、颞极、楔前叶）。使用具有固定因素条件和时间的线性混合效应模型进行数据分析。结果 PANAS 积极情感量表显示在 LIIE 和 HIIE 后显着增加，而在对照条件后消极情感显着减少。在 rs-fMRI 中，杏仁核和全脑之间没有观察到显着的随时间变化的相互作用。杏仁核-楔前叶 FC 分析显示出交互作用，表明控制条件后运动后的反相关性降低，但运动条件下的反相关性稳定，甚至略有增强，尤其是 HIIE。 讨论 总之，LIIE 和 HIIE 对情绪和情绪都有积极影响。对杏仁核-楔前叶 FC 的伴随影响，特别是在 HIIE 之后。尽管未发现杏仁核-楔前叶 FC 和 PANAS 之间存在显着相关性，但应在已观察到杏仁核-楔前叶 FC 异常的情感障碍的背景下讨论结果。