The design of efficient electrocatalysts for the determination of chlorogenic acids (CGA) is crucial in the biological and medical fields. In this paper, ZIF-67/poly(3,4-ethylenedioxythiophene) (PEDOT) nanocomposites were synthesised. The introduction of PEDOT increased the electrical conductivity of the ZIF-67/PEDOT composites, inhibited the Co atom agglomeration, led to the exposure of more active sites and increased the transport channels. An ultrasensitive CGA sensor based on ZIF-67/PEDOT nanocomposite modified carbon paper (CP) electrode was developed. The nanomaterials were characterised using scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray diffraction spectroscopy (XRD). Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used to study the electrochemical properties of the modified CP electrode. In addition, the effects of different experimental conditions such as pH, scan rate and concentration on the peak current of CGA were investigated. Under the optimised conditions, the linear range of ZIF-67/PEDOT/CP for the determination of CGA was 0.1 ∼ 40 μM, and the limit of detection (LOD) was as low as 0.003 μM (S/N = 3). Furthermore, the sensor was successfully used for the quantitative analysis of CGA in real samples.

中文翻译：

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ZIF-67/PEDOT 修饰碳纸电极用于灵敏电化学测定绿原酸

设计用于测定绿原酸（CGA）的高效电催化剂在生物和医学领域至关重要。本文合成了ZIF-67/聚(3,4-乙烯二氧噻吩)(PEDOT)纳米复合材料。 PEDOT的引入提高了ZIF-67/PEDOT复合材料的电导率，抑制了Co原子的团聚，导致更多的活性位点暴露并增加了传输通道。开发了一种基于ZIF-67/PEDOT纳米复合材料改性碳纸（CP）电极的超灵敏CGA传感器。使用扫描电子显微镜（SEM）、透射电子显微镜（TEM）和X射线衍射光谱（XRD）对纳米材料进行了表征。采用循环伏安法（CV）和微分脉冲伏安法（DPV）研究了修饰CP电极的电化学性能。此外，还研究了不同实验条件（例如pH、扫描速率和浓度）对CGA峰值电流的影响。在优化条件下，ZIF-67/PEDOT/CP测定CGA的线性范围为0.1～40μM，检测限(LOD)低至0.003μM(S/N=3)。此外，该传感器还成功用于实际样品中CGA的定量分析。