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Diagnostic accuracy of non-invasive tests to screen for at-risk MASH—An individual participant data meta-analysis
Liver International ( IF 6.7 ) Pub Date : 2024-04-04 , DOI: 10.1111/liv.15914
Ferenc E. Mózes 1 , Jenny A. Lee 2 , Yasaman Vali 2 , Emmanuel A. Selvaraj 1, 3, 4 , Arjun N. A. Jayaswal 1 , Jérôme Boursier 5, 6 , Victor de Lédinghen 7, 8 , Monica Lupșor‐Platon 9 , Yusuf Yilmaz 10, 11 , Wah‐Kheong Chan 12 , Sanjiv Mahadeva 12 , Thomas Karlas 13 , Johannes Wiegand 13 , Shalimar 14 , Emmanouil Tsochatzis 15 , Antonio Liguori 15, 16 , Vincent Wai‐Sun Wong 17 , Dae Ho Lee 18 , Adriaan G. Holleboom 19 , Anne‐Marieke van Dijk 19 , Anne Linde Mak 19 , Hannes Hagström 20, 21 , Camilla Akbari 21 , Masashi Hirooka 22 , Dong Hyeon Lee 23 , Won Kim 23 , Takeshi Okanoue 24 , Toshihide Shima 24 , Atsushi Nakajima 25 , Masato Yoneda 25 , Paul J. Thuluvath 26, 27 , Feng Li 26 , Annalisa Berzigotti 28, 29 , Yuly P. Mendoza 28, 30 , Mazen Noureddin 31 , Emily Truong 32 , Céline Fournier‐Poizat 33 , Andreas Geier 34 , Theresa Tuthill 35 , Carla Yunis 36 , Quentin M. Anstee 37, 38 , Stephen A. Harrison 1 , Patrick M. Bossuyt 2 , Michael Pavlides 1, 3, 4
Affiliation  

There is a need to reduce the screen failure rate (SFR) in metabolic dysfunction-associated steatohepatitis (MASH) clinical trials (MASH+F2-3; MASH+F4) and identify people with high-risk MASH (MASH+F2-4) in clinical practice. We aimed to evaluate non-invasive tests (NITs) screening approaches for these target conditions.

中文翻译:

用于筛查高危 MASH 的非侵入性测试的诊断准确性——个体参与者数据荟萃分析

需要降低代谢功能障碍相关脂肪性肝炎 (MASH) 临床试验 (MASH+F2-3; MASH+F4) 中的筛查失败率 (SFR) 并识别高危 MASH 人群 (MASH+F2-4)在临床实践中。我们的目的是评估针对这些目标病症的非侵入性测试(NIT)筛查方法。
更新日期:2024-04-05
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