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Base-promoted synthesis of 3-arylquinolines using DMSO as C1 source
Tetrahedron Letters ( IF 1.8 ) Pub Date : 2024-04-02 , DOI: 10.1016/j.tetlet.2024.155044
Muhammad Asif Iqbal , Ali Raza Shah , Ruimao Hua

The synthesis of 3-arylquinolines through a cyclocondensation of 2-aminoarylmethanols and benzaldehydes in DMSO promoted by KOBu has been developed. In this procedure, DMSO is used not only as a solvent, but also a C1 source incorporated into the 2-position of quinoline ring.

中文翻译:

使用 DMSO 作为 C1 源的碱促进合成 3-芳基喹啉

已经开发出通过 2-氨基芳基甲醇和苯甲醛在 DMSO 中由 KOBu 促进环缩合合成 3-芳基喹啉的方法。在此过程中,DMSO 不仅用作溶剂,还用作掺入喹啉环 2 位的 C1 源。
更新日期:2024-04-02
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