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T266M variants of ANGPTL4 improve lipid metabolism by modifying their binding affinity to acetyl-CoA carboxylase in obstructive sleep apnea
Annals of Medicine ( IF 4.4 ) Pub Date : 2024-04-04 , DOI: 10.1080/07853890.2024.2337740
Xinyi Li 1 , Chenyang Li 1 , Wenjun Xue 2 , Zhicheng Wei 1 , Hangdong Shen 1 , Kejia Wu 1 , Huaming Zhu 1 , Huajun Xu 1 , Xiaolin Wu 3 , Hongliang Yi 1 , Jian Guan 1 , Shankai Yin 1
Affiliation  

Angiopoietin-like protein 4 (ANGPTL4) is recognized as a crucial regulator in lipid metabolism. Acetyl-CoA carboxylases (ACACAs) play a role in the β-oxidation of fatty acids. Yet, the functions of...

中文翻译:

ANGPTL4 的 T266M 变体通过改变阻塞性睡眠呼吸暂停中乙酰辅酶 A 羧化酶的结合亲和力来改善脂质代谢

血管生成素样蛋白 4 (ANGPTL4) 被认为是脂质代谢的重要调节因子。乙酰辅酶A羧化酶(ACACAs)在脂肪酸的β-氧化中发挥作用。然而,功能...
更新日期:2024-04-08
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