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Initial Experiences with the Trenza Embolization Device for the Treatment of Wide-Neck Intracranial Aneurysms: A 12-Patient Case Series
American Journal of Neuroradiology ( IF 3.5 ) Pub Date : 2024-04-01 , DOI: 10.3174/ajnr.a8153
Rahul Raj , Jussi Numminen

SUMMARY:

The Trenza embolization device is a frame coil implant with flow-disruption properties and is a new alternative to treat challenging mid-to-large-sized broad-neck bifurcation or sidewall aneurysms. We conducted an observational single-center retrospective study of 12 consecutive patients treated for 10 unruptured and 2 ruptured 6- to 12-mm broad-neck bifurcation or sidewall aneurysms with the Trenza device during 2022–2023. The median patient age was 64 years (interquartile range, 59–70 years), 58% were women, the median largest aneurysm diameter was 9.6 mm (interquartile range, 7.5–11.9 mm), the median dome-to-neck ratio was 1.8 (interquartile range, 1.6–1.9), the most common aneurysm locations were the anterior communicating artery (33%) and basilar artery tip (33%). After a median follow-up of 6.5 months, adequate aneurysm occlusion was achieved in 83%. There were 3 major ischemic complications (25%), leading to 2 permanent neurologic deficits (17%) and 1 transient neurologic deficit (8%). There was 1 fatal rupture of a treated aneurysm 1.6 months after the index treatment. Two patients were retreated (17%). Ischemic complications occurred in patients after a too-dense coil packing at the base of the aneurysm. No technical issues related to the device were encountered. In summary, an adequate aneurysm occlusion rate was achieved using the Trenza-assisted coiling technique for otherwise challenging mid-to-large-sized broad-neck aneurysms. Ischemic complications seemed to occur following overdense coiling at the base of the aneurysm.



中文翻译:

Trenza 栓塞装置治疗宽颈颅内动脉瘤的初步经验:12 例病例系列

概括:

Trenza 栓塞装置是一种具有血流中断特性的框架线圈植入物,是治疗具有挑战性的中型至大型宽颈分叉或侧壁动脉瘤的新替代方案。我们对 2022 年至 2023 年间使用 Trenza 装置治疗 10 例未破裂和 2 例破裂的 6 至 12 毫米宽颈分叉或侧壁动脉瘤的 12 名连续患者进行了一项观察性单中心回顾性研究。患者中位年龄为 64 岁(四分位距,59-70 岁),58% 为女性,最大动脉瘤直径中位为 9.6 毫米(四分位距,7.5-11.9 毫米),中位穹颈比为 1.8 (四分位数范围,1.6-1.9),最常见的动脉瘤位置是前交通动脉(33%)和基底动脉尖端(33%)。中位随访 6.5 个月后,83% 的患者实现了充分的动脉瘤闭塞。共有 3 例主要缺血性并发症 (25%),导致 2 例永久性神经功能缺损 (17%) 和 1 例短暂性神经功能缺损 (8%)。在首次治疗后 1.6 个月,有 1 例治疗后的动脉瘤发生致命破裂。两名患者接受治疗(17%)。动脉瘤底部线圈填充过密后,患者会出现缺血性并发症。没有遇到与设备相关的技术问题。总之,对于其他具有挑战性的中型至大型宽颈动脉瘤,使用 Trenza 辅助弹簧圈栓塞技术实现了足够的动脉瘤闭塞率。动脉瘤底部过度致密缠绕后似乎会发生缺血性并发症。

更新日期:2024-04-01
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