Activation energy and thermal radiation as a means of heat transfer are significant and fascinating phenomena for scientists and researchers because of their significance in cancer treatment. As a result, heat kills cancer cells and shrinks tumors, making hyperthermia therapy a cutting-edge cancer treatment. This paper examines the peristaltic motion of a Johnson–Segalman nanofluid across an asymmetric pliable microchannel under the impact of activation energy. We obtained the governing equations for the non-Newtonian nanofluid. Partial differential equations (PDEs) are reduced to ordinary differential equations (ODEs) under the assumption of large wavelengths and tiny Reynolds number assumptions. The flow patterns and trapping phenomena were numerically generated using the NDSolve command of the computational mathematical software Mathematica. The influence of important liquid parameters was examined with graphical representations of the results. The current study reveals an enhancement in the heat generation parameter, an enhancement in the temperature and a reduction in the concentration.

活化能和热辐射作为传热手段对于科学家和研究人员来说是重要且令人着迷的现象，因为它们在癌症治疗中具有重要意义。因此，热量可以杀死癌细胞并缩小肿瘤，使热疗成为一种尖端的癌症治疗方法。本文研究了约翰逊-西格曼纳米流体在活化能的影响下穿过不对称柔韧微通道的蠕动运动。我们获得了非牛顿纳米流体的控制方程。在大波长和微小雷诺数假设的情况下，偏微分方程 (PDE) 被简化为常微分方程 (ODE)。使用计算数学软件 Mathematica 的 NDSolve 命令以数值方式生成流动模式和捕获现象。通过结果的图形表示来检查重要液体参数的影响。目前的研究揭示了产热参数的增强、温度的升高和浓度的降低。