Paediatric autoimmune encephalitis (e.g., acute disseminated encephalomyelitis, N-methyl-D-aspartate receptor antibody encephalitis) is an inflammatory brain disease that causes cognitive deficits, psychiatric symptoms, seizures, MRI, and EEG abnormalities. Patients can continue to experience residual cognitive difficulties months to years after the acute illness. Magnetoencephalography (MEG) can examine neural changes in the absence of frank structural abnormalities and may help identify factors predicting children at risk of long-term cognitive deficits. We predicted that theta and delta brain functional connectivity networks would be associated with processing speed and working memory in children with autoimmune encephalitis.

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通过脑磁图将儿童自身免疫性脑炎的大脑网络与认知联系起来

儿童自身免疫性脑炎（例如急性播散性脑脊髓炎、N-甲基-D-天冬氨酸受体抗体脑炎）是一种炎症性脑部疾病，可导致认知缺陷、精神症状、癫痫发作、MRI 和脑电图异常。急性疾病发生后数月至数年，患者可能会继续经历残留的认知困难。脑磁图（MEG）可以在没有明显结构异常的情况下检查神经变化，并可能有助于识别预测儿童存在长期认知缺陷风险的因素。我们预测 θ 和 δ 大脑功能连接网络将与患有自身免疫性脑炎的儿童的处理速度和工作记忆相关。