Ellagitannins, a class of polyphenols with divergent structures, have attracted considerable attention from synthetic organic chemists. The basic structures in ellagitannins contain esters of D-glucose with galloyl or hexahydroxyldiphenoyl groups, as well as diaryl ether structures. Thus, the synthesis methodologies of such components have been developed by various groups, including our group. This review describes the synthetic methods reported by our group during 2017–2023, aimed at increasing the number of ellagitannins that can be chemically synthesized. In addition, recent related reports are introduced.

Fullsize Image

中文翻译：

---

鞣花单宁统一合成方法学的发展

鞣花单宁是一类具有不同结构的多酚，引起了有机合成化学家的广泛关注。鞣花单宁的基本结构包含 D-葡萄糖与没食子酰基或六羟基联苯酰基的酯，以及二芳基醚结构。因此，包括我们小组在内的各个小组已经开发了此类成分的合成方法。本综述描述了我们小组在 2017 年至 2023 年期间报告的合成方法，旨在增加可化学合成的鞣花单宁的数量。此外，还介绍了近期的相关报道。

全尺寸图像