Fructoborates are essential nutritional compounds which have garnered significant attention, due to their impact on human health. Recent studies have also identified fructoborates in other sources, such as certain leafy greens, tubers and medicinal plants, such as ginseng roots. This review delves into the intricacies of their natural occurrence, chemical properties and the myriad of health benefits associated with their consumption. Particular emphasis is placed on calcium fructoborate, given its high content of boron, calcium and fructose, and its profound effects on bone health, cardiovascular function, metabolic syndrome and inflammation. Advanced analytical methods, including spectroscopy and chromatography, are also discussed for their role in detecting and quantifying fructoborates in dietary supplements and other matrices. The review concludes with a look at future research directions, emphasizing the need for further studies on their bioavailability, absorption mechanisms long-term safety and efficacy. However, it is important to mention that there is a predominant focus on recent studies regarding boron and boric acid, with fewer studies concentrating on the specific effects of fructoborates. Additionally, the significant variability at the individual level in response to fructoborates may pose a challenge, considering that individual reactions can vary based on genetic factors, lifestyle and overall health status. Certainly, the evolving research landscape surrounding fructoborates suggests a promising avenue for exploring their potential applications in the development of novel therapeutics and dietary interventions.

果硼酸盐是必需的营养化合物，由于其对人类健康的影响而受到广泛关注。最近的研究还在其他来源中发现了果硼酸盐，例如某些绿叶蔬菜、块茎和药用植物（例如人参根）。这篇评论深入探讨了它们的自然发生、化学特性以及与其消费相关的无数健康益处的复杂性。鉴于其硼、钙和果糖含量高，以及对骨骼健康、心血管功能、代谢综合征和炎症的深远影响，果糖硼酸钙受到特别重视。还讨论了包括光谱法和色谱法在内的先进分析方法在检测和定量膳食补充剂和其他基质中果硼酸盐方面的作用。该综述最后展望了未来的研究方向，强调需要进一步研究其生物利用度、吸收机制、长期安全性和有效性。然而，值得一提的是，最近的研究主要集中在有关硼和硼酸的方面，而很少有研究集中在果糖硼酸盐的具体作用上。此外，考虑到个体反应可能因遗传因素、生活方式和整体健康状况而异，个体水平对果硼酸盐的反应存在显着差异可能会带来挑战。当然，围绕果硼酸盐不断发展的研究前景为探索其在开发新型疗法和饮食干预方面的潜在应用提供了一条有前途的途径。