Background/ObjectivesOncoplastic reconstruction (IOR) performed in conjunction with breast conserving therapy (BCT) has been found to improve psychosocial well‐being, reduce hospitalization time, and reduce cost burden. Few studies have looked at the safety profile, complication rates, and overall outcomes in patients ages 65 years and older undergoing IOR versus BCT alone.MethodsA retrospective, cross‐sectional, single‐institution medical record review was conducted of women diagnosed with breast cancer age 65 years or older who received IOR or BCT alone. Demographics, clinical data, and major and minor complication profiles were compared between cohorts.ResultsA total of 310 patients were included. Of these, 126 received IOR, while 184 received BCT alone. Age >85 was found to have a significantly higher risk for any complication and was an independent predictor for experiencing any complication (OR: 8.5, p = 0.015; OR: 1.06, p = 0.029). Major complication rates were significantly higher in the BCT cohort (16.9% vs. 7.9%, p = 0.023).ConclusionIOR in the elderly is a safe option and was not found to be a predictor of experiencing higher complications. Patients who are 85 years and older had a higher risk of complications, and future studies may explore risk‐benefit in that particular cohort of patients in which BCT is planned.

中文翻译：

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老年人保乳治疗的肿瘤整形重建与单纯保乳治疗的比较

背景/目标肿瘤整形重建 (IOR) 与保乳治疗 (BCT) 结合进行已被发现可以改善社会心理健康、减少住院时间并减轻费用负担。很少有研究关注 65 岁及以上患者接受 IOR 与单独 BCT 的安全性、并发症发生率和总体结果。方法对诊断为乳腺癌的女性进行回顾性、横断面、单机构病历审查65 岁或以上仅接受 IOR 或 BCT 的人。对队列之间的人口统计学、临床数据以及主要和次要并发症情况进行比较。结果总共纳入 310 名患者。其中，126 人接受了 IOR，而 184 人仅接受了 BCT。研究发现，年龄 >85 岁出现任何并发症的风险显着较高，并且是发生任何并发症的独立预测因素（OR：8.5，p= 0.015；或：1.06，p= 0.029）。 BCT 队列的主要并发症发生率显着更高（16.9% vs. 7.9%，p= 0.023）。结论 IOR 对于老年人来说是一种安全的选择，并且没有发现它是发生更高并发症的预测因素。 85 岁及以上的患者出现并发症的风险较高，未来的研究可能会探讨计划进行 BCT 的特定患者群体的风险效益。