Plasmodium ovale malaria is usually considered a tropical infectious disease associated with low morbidity and mortality. However, severe disease and death have previously been reported. A case of severe P. ovale malaria in a healthy Caucasian man with a triangle splenic infarction and clinical progression towards Acute Respiratory Distress Syndrome was reported despite a rapid response to oral chloroquine treatment with 24-h parasitaemia clearance. Plasmodium ovale malaria is generally considered as a benign disease, with low parasitaemia. However, severe disease and death have occasionally been reported. It is important to be aware that occasionally it can progress to serious illness and death even in immunocompetent individuals.

中文翻译：

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一名在意大利就诊的男性旅客患有严重卵形疟原虫疟疾并伴有急性呼吸窘迫综合征和脾梗塞

卵形疟原虫疟疾通常被认为是一种发病率和死亡率较低的热带传染病。然而，此前已有严重疾病和死亡的报道。据报道，一名健康白种人患有严重的卵形疟原虫，患有三角脾梗塞，尽管口服氯喹治疗反应迅速，24 小时寄生虫血症清除，但临床进展为急性呼吸窘迫综合征。卵形疟原虫疟疾通常被认为是一种良性疾病，寄生虫血症较低。然而，偶尔也有严重疾病和死亡的报道。重要的是要意识到，即使是免疫功能正常的个体，有时也会发展为严重疾病甚至死亡。