Background Limited data are available on the effects of the COVID-19 pandemic on health-related indicators in sub-Saharan Africa. This study aimed to estimate the effect of the COVID-19 pandemic on nine indicators of HIV, malaria and tuberculosis (TB) in Togo. Methods For this interrupted time series analysis, national health information system data from January 2019 to December 2021 and TB programmatic data from the first quarter of 2018 to the fourth quarter of 2022 were analysed. Nine indicators were included. We used Poisson segmented regression to estimate the immediate impact of the pandemic and per-pandemic period trends through incidence rate ratios (IRRs) with 95% CIs. Results Overall, there was a decrease in six of the nine indicators, ranging from 19.3% (IRR 0.807, 95% CI 0.682 to 0.955, p=0.024) for the hospitalisation of patients for malaria to 36.9% (IRR 0.631, 95% CI 0.457 to 0.871, p=0.013) for TB diagnosis by Mycobacterium tuberculosis Xpert immediately after the declaration of the COVID-19 pandemic. A comparison of the observed and predicted trends showed that the trend remained constant between the prepandemic and pandemic periods of COVID-19 for all malaria indicators. A significant downward monthly trend was observed in antiretroviral therapy initiation (IRR 0.909, 95% CI 0.892 to 0.926, p<0.001) and positive TB microscopy (IRR 0.919, 95% CI 0.880 to 0.960, p=0.002). Conclusion HIV, malaria and TB services were generally maintained over time in Togo despite the COVID-19 pandemic. However, given the decline in levels immediately after the onset of the pandemic, there is an urgent need to improve the preparedness of the healthcare system. Data may be obtained from a third party and are not publicly available.

中文翻译：

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COVID-19 大流行对多哥艾滋病毒、疟疾和结核病指标的影响：间断时间序列分析

背景 关于 COVID-19 大流行对撒哈拉以南非洲地区健康相关指标影响的数据有限。本研究旨在评估 COVID-19 大流行对多哥艾滋病毒、疟疾和结核病 (TB) 九项指标的影响。方法 对于这种间断时间序列分析，分析了 2019 年 1 月至 2021 年 12 月的国家卫生信息系统数据和 2018 年第一季度至 2022 年第四季度的结核病规划数据。其中包括九项指标。我们使用泊松分段回归通过 95% CI 的发病率比 (IRR) 来估计大流行和大流行期间趋势的直接影响。结果 总体而言，九项指标中有六项下降，从疟疾住院患者的 19.3%（IRR 0.807，95% CI 0.682 至 0.955，p=0.024）到 36.9%（IRR 0.631，95% CI）。 0.457 至 0.871，p=0.013）在宣布 COVID-19 大流行后立即通过结核分枝杆菌 Xpert 进行结核病诊断。观察到的趋势和预测的趋势的比较表明，所有疟疾指标的趋势在 COVID-19 流行前和大流行期间保持不变。抗逆转录病毒治疗开始（IRR 0.909，95% CI 0.892 至 0.926，p<0.001）和结核病镜检阳性（IRR 0.919，95% CI 0.880 至 0.960，p=0.002）观察到每月显着下降的趋势。结论 尽管发生了 COVID-19 大流行，多哥的艾滋病毒、疟疾和结核病服务总体上仍得到维持。然而，鉴于大流行爆发后水平立即下降，迫切需要改善医疗保健系统的准备情况。数据可能从第三方获得，并且不公开。