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Hypothalamic TRPM8 and TRPA1 ion channel genes in the regulation of temperature homeostasis at water balance changes
Neuroscience Letters ( IF 2.5 ) Pub Date : 2024-04-03 , DOI: 10.1016/j.neulet.2024.137763
T.V. Kozyreva , I.V. Orlov , A.R. Boyarskaya , I.P. Voronova

The role of the hypothalamic cold-sensitive ion channels - transient receptor potential melastatin 8 (TRPM8) and transient receptor potential ankyrin 1 (TRPA1) in homeostatic systems of thermoregulation and water-salt balance – is not clear. The interaction of homeostatic systems of thermoregulation and water-salt balance without additional temperature load did not receive due attention, too. On the models of water-balance disturbance, we tried to elucidate some aspect of these problems.

中文翻译:

下丘脑TRPM8和TRPA1离子通道基因在水平衡变化时调节温度稳态

下丘脑冷敏感离子通道——瞬态受体电位美塑蛋白 8 (TRPM8) 和瞬态受体电位锚蛋白 1 (TRPA1) 在体温调节和水盐平衡稳态系统中的作用尚不清楚。在没有额外温度负荷的情况下,温度调节和水盐平衡的稳态系统的相互作用也没有受到应有的关注。在水平衡扰动模型上,我们试图阐明这些问题的某些方面。
更新日期:2024-04-03
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