Neural activity can increase the length of nodes of Ranvier (NOR) and slow impulse transmission; however, little is known about the biologically and clinically important recovery process. Sensory deprivation promotes neural plasticity in many phenomena, raising the question of whether recovery of NOR morphology is influenced by sensory deprivation. The results show that NOR gap length recovery in mouse optic nerve was not affected significantly by binocular visual deprivation imposed by maintaining mice in 24 hr dark for 30 days compared to mice recovering under normal visual experience. The findings provide insight into the cellular mechanism of NOR plasticity.

中文翻译：

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视觉剥夺下视神经朗飞结构结节的恢复

神经活动可以增加朗飞结（NOR）的长度并减慢脉冲传输；然而，人们对生物学和临床上重要的恢复过程知之甚少。感觉剥夺在许多现象中促进神经可塑性，这就提出了 NOR 形态的恢复是否受到感觉剥夺影响的问题。结果表明，与在正常视觉体验下恢复的小鼠相比，将小鼠维持在 24 小时黑暗中 30 天所施加的双眼视觉剥夺不会显着影响小鼠视神经 NOR 间隙长度的恢复。这些发现提供了对 NOR 可塑性细胞机制的深入了解。