Mesenchymal stem cells (MSCs) have high priority in clinical applications for treatment of immune disorders because of their immunomodulatory function. A lot of researches have currently been undertaken to enhance the stemness capacities of the cells and pick an excellent type of MSCs for clinical approaches. This study aims to assess the immunomodulatory related MicroRNAs (miRNAs) expression as well as their target genes in both adipose derived stem cells (Ad-SCs) and dental pulp derived stem cell (DP-SCs) in the presence or lack of Crocin (saffron plant's bioactive compound).

中文翻译：

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通过 microRNA-155、microRNA-21、microRNA-23b、microRNA-126a 及其靶炎症基因的表达调节，间充质干细胞在藏红花素治疗中的免疫调节特性

间充质干细胞（MSC）因其免疫调节功能而在治疗免疫性疾病的临床应用中具有高度优先性。目前已经开展了大量研究来增强细胞的干细胞能力，并为临床方法选择优良的间充质干细胞类型。本研究旨在评估在存在或缺乏藏红花素的情况下，脂肪源性干细胞 (Ad-SCs) 和牙髓源性干细胞 (DP-SCs) 中免疫调节相关的 MicroRNA (miRNA) 表达及其靶基因植物的生物活性化合物）。