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Plant‐Derived Coumarins: A Narrative Review Of Their Structural And Biomedical Diversity
Chemistry & Biodiversity ( IF 2.9 ) Pub Date : 2024-04-08 , DOI: 10.1002/cbdv.202400344
Areej Hazem Younes 1 , Yasser Fakri Mustafa 2
Affiliation  

Plant‐derived coumarin (PDC) is a naturally occurring heterocyclic backbone that belongs to the benzopyrone family. PDC and its based products are characterized by low toxicity and high distribution in a variety of herbal treatments that have numerous therapeutic potentials. These include anticoagulants, antibacterials, anti‐inflammatory agents, anticancer agents, antioxidants, and others. So, it may be appropriate to investigate the qualities and potential bioactivities of PDCs. This article provides an overview of the biomedical potentials, availability, and clinical use possibilities of PDCs, with a focus on their important modes of action, using information on various pharmacological qualities discovered. The data used in this study came from published research between 2015 and 2023. We reviewed a selection of databases, including PubMed, Scopus, Web of Science, and Google Scholar, during that period. In conclusion, because of their abundance in medicinal plants, the clinical biochemistry attributes of PDCs are currently of interest. In a variety of medical specialties, PDCs serve a useful role as therapeutic agents.

中文翻译:

植物源香豆素:对其结构和生物医学多样性的叙述性回顾

植物源香豆素 (PDC) 是一种天然存在的杂环骨架,属于苯并吡喃酮家族。 PDC 及其基础产品的特点是低毒性和在多种草药治疗中的高分布,具有许多治疗潜力。其中包括抗凝剂、抗菌剂、抗炎剂、抗癌剂、抗氧化剂等。因此,研究 PDC 的品质和潜在生物活性可能是合适的。本文利用已发现的各种药理学特性的信息,概述了 PDC 的生物医学潜力、可用性和临床使用可能性,重点关注其重要的作用模式。本研究使用的数据来自 2015 年至 2023 年期间发表的研究。我们回顾了该时期的一系列数据库,包括 PubMed、Scopus、Web of Science 和 Google Scholar。总之,由于药用植物丰富,PDC 的临床生化属性目前引起人们的兴趣。在各种医学专业中,PDC 作为治疗剂发挥着有用的作用。
更新日期:2024-04-08
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