Metastatic cancer represents the main cause of death in patients with cancer. However, basic and translational research is hampered by the limited availability of metastatic samples. In this context, post-mortem tissue donation programmes represent a complementary and attractive solution. Here, we highlight the opportunities and challenges, and outline why we believe this represents a global effort. Metastatic cancer represents the main cause of death in patients with cancer, but metastasis research is hindered by the limited availability of metastatic samples. In this Comment, Desmedt and Carey highlight the opportunities and challenges of post-mortem tissue donation programmes, which represent a complementary and attractive solution to overcome many of the hurdles in metastasis research.

中文翻译：

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全球尸检组织捐赠计划加速癌症研究

转移性癌症是癌症患者死亡的主要原因。然而，基础和转化研究因转移样本的有限性而受到阻碍。在这种情况下，死后组织捐赠计划代表了一种补充且有吸引力的解决方案。在这里，我们强调机遇和挑战，并概述为什么我们相信这代表了全球的努力。转移性癌症是癌症患者死亡的主要原因，但转移性研究因转移性样本的有限性而受到阻碍。在这篇评论中，德斯梅特和凯里强调了死后组织捐赠计划的机遇和挑战，该计划代表了克服转移研究中许多障碍的补充和有吸引力的解决方案。