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Photothermal therapy: a novel potential treatment for prostate cancer
Biomaterials Science ( IF 6.6 ) Pub Date : 2024-04-09 , DOI: 10.1039/d4bm00057a
Zirui Dong 1 , Kaming Xue 2 , Anushikha Verma 3 , Jian Shi 1 , Zhihao Wei 1 , Xiaotian Xia 4 , Keshan Wang 1 , Xiaoping Zhang 1
Affiliation  

Prostate cancer (PCa) is a leading cause of cancer-related death in men, and most PCa patients treated with androgen deprivation therapy will progress to metastatic castration-resistant prostate cancer (mCRPC) due to the lack of efficient treatment. Recently, lots of research indicated that photothermal therapy (PTT) was a promising alternative that provided an accurate and efficient prostate cancer therapy. A photothermic agent (PTA) is a basic component of PPT and is divided into organic and inorganic PTAs. Besides, the combination of PTT and other therapies, such as photodynamic therapy (PDT), immunotherapy (IT), chemotherapy (CT), etc., provides an more efficient strategy for PCa therapy. Here, we introduce basic information about PTT and summarize the PTT treatment strategies for prostate cancer. Based on recent works, we think the combination of PPT and other therapies provides a novel possibility for PCa, especially CRPC clinical treatment.

中文翻译:

光热疗法:前列腺癌的一种新型潜在治疗方法

前列腺癌(PCa)是男性癌症相关死亡的主要原因,大多数接受雄激素剥夺治疗的PCa患者由于缺乏有效的治疗,将进展为转移性去势抵抗性前列腺癌(mCRPC)。最近,大量研究表明光热疗法(PTT)是一种有前途的替代方案,可以提供准确有效的前列腺癌治疗。光热剂(PTA)是PPT的基本成分,分为有机PTA和无机PTA。此外,PTT与其他疗法如光动力疗法(PDT)、免疫疗法(IT)、化疗(CT)的结合,为PCa治疗提供了更有效的策略。在此,我们介绍PTT的基本信息,并总结前列腺癌的PTT治疗策略。基于最近的工作,我们认为PPT与其他疗法的结合为PCa,特别是CRPC的临床治疗提供了新的可能性。
更新日期:2024-04-09
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