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Transforming Pharmaceutical Synthesis with Sein‐E‐B Nanocomposite Photocatalyst through 1,4‐NAD(P)H Cofactor Regeneration and C‐N Bond Activation
Chemistry & Biodiversity ( IF 2.9 ) Pub Date : 2024-04-09 , DOI: 10.1002/cbdv.202400329
Ravindra Shukla 1 , Rajesh Yadav 2 , vitthal Gole 3 , Rajat Singhal 2 , Rehana Shahin 2 , Shaifali Mishra 2 , Satyam Singh 2 , Kanchan Sharma 2 , Jin-Ook Baeg 4 , Gamal El-Hiti 5 , Krishna Yadav 6 , Navneet Kumar Gupta 7
Affiliation  

The need for sunlight chemical renewal and contemporary organic transformation has fostered the advancement of environmentally friendly photocatalytic techniques. For the first time, we report on the novel crafting of a bright future with selenium‐infused Eosin‐B (Sein‐E‐B) nanocomposite photocatalysts in this work. The Sein‐E‐B nanocomposite materials were created using a hydrothermal process for solar chemical regeneration and organic transformation under visible light. The synthesized samples were subjected to UV‐DRS‐visible spectroscopy, FT‐IR, SEM, EDX, EIS and XRD analysis. The energy band gap of the Sein‐E‐B nanocomposite photocatalyst was measured using UV‐DRS, and the result was around 2.06 eV. to investigate the generated Sein‐E‐B catalytic activity as a nanocomposite for 1,4‐NADH/NADPH re‐formation and C‐N bond activation. This novel photocatalyst offers a promising alternative for the regeneration of solar chemicals and C–N bond creation between pyrrole and aryl halides.

中文翻译:

Sein-E-B 纳米复合光催化剂通过 1,4-NAD(P)H 辅因子再生和 C-N 键激活改变药物合成

对阳光化学更新和当代有机转化的需求促进了环保光催化技术的进步。在这项工作中,我们首次报道了利用注入硒的 Eosin-B (Sein-E-B) 纳米复合光催化剂创造光明未来的新颖方法。 Sein-E-B 纳米复合材料是利用水热工艺在可见光下进行太阳能化学再生和有机转化而制成的。合成的样品进行了紫外-DRS-可见光谱、FT-IR、SEM、EDX、EIS 和 XRD 分析。使用UV-DRS测量Sein-E-B纳米复合光催化剂的能带隙,结果约为2.06 eV。研究生成的 Sein-E-B 作为纳米复合材料对 1,4-NADH/NADPH 重组和 C-N 键活化的催化活性。这种新型光催化剂为太阳能化学品的再生以及吡咯和芳基卤化物之间 C-N 键的形成提供了一种有前景的替代方案。
更新日期:2024-04-09
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