:: Flavonoids are a class of polyphenolic compounds that can be classified into six distinct categories, namely isoflavonoids, flavanones, flavanols, flavonols, flavones, and anthocyanidins. These compounds are naturally occurring and can be found in a diverse range of plant species. Flavonoids, a class of bioactive compounds, are mostly obtained through the consumption of vegetables, fruits and plant-derived beverages such as wine, cocoa-based products and green tea. Flavonoids have been demonstrated to exhibit a diverse range of anticancer properties. These include the modulation of activities of enzymes involved in scavenging reactive oxygen species, involvement in cell cycle arrest, induction of apoptosis and autophagy, as well as suppression of cancer cell proliferation and invasiveness. Flavonoids exhibit a dual role in maintaining reactive oxygen species balance. They function as antioxidants in regular physiological conditions, while also demonstrating significant pro-oxidant properties in cancer cells. This prooxidant activity induces apoptotic pathways and downregulates pro-inflammatory signalling pathways. The paper explores the biochemical characteristics, bioavailability, anticancer efficacy, and modes of action of flavonoids.

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探索类黄酮在癌症治疗中的治疗潜力

* 类黄酮是一类多酚化合物，可分为六种不同的类别，即异黄酮、黄烷酮、黄烷醇、黄酮醇、黄酮和花青素。这些化合物是天然存在的，可以在多种植物物种中找到。类黄酮是一类生物活性化合物，主要通过食用蔬菜、水果和植物源饮料（例如葡萄酒、可可产品和绿茶）获得。类黄酮已被证明具有多种抗癌特性。这些包括调节参与清除活性氧、参与细胞周期停滞、诱导细胞凋亡和自噬以及抑制癌细胞增殖和侵袭的酶的活性。类黄酮在维持活性氧平衡方面具有双重作用。它们在正常生理条件下发挥抗氧化剂的作用，同时在癌细胞中也表现出显着的促氧化特性。这种促氧化活性可诱导细胞凋亡途径并下调促炎症信号传导途径。本文探讨了类黄酮的生化特性、生物利用度、抗癌功效和作用方式。