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Cutting-edge approaches for targeted drug delivery in breast cancer: beyond conventional therapies
Nanoscale Advances ( IF 4.7 ) Pub Date : 2024-04-10 , DOI: 10.1039/d4na00086b
Ramesh Chaudhari 1 , Vishva Patel 1 , Ashutosh Kumar 1
Affiliation  

Breast cancer is a global health challenge with staggering statistics underscoring its pervasive impact. The burden of this disease is measured in terms of its prevalence and the challenges it poses to healthcare systems, necessitating a closer look at its epidemiology and impact. Current breast cancer treatments, including surgery, chemotherapy, radiation therapy, and targeted therapies, have made significant strides in improving patient outcomes. However, they are not without limitations, often leading to adverse effects and the development of drug resistance. This comprehensive review delves into the complex landscape of breast cancer, including its incidence, current treatment modalities, and the inherent limitations of existing therapeutic approaches. It also sheds light on the promising role of nanotechnology, encompassing both inorganic and organic nanoparticles equipped with the ability to selectively deliver therapeutic agents to tumor sites, in the battle against breast cancer. The review also addresses the emerging therapies, their associated challenges, and the future prospects of targeted drug delivery in breast cancer management.

中文翻译:

乳腺癌靶向药物输送的尖端方法:超越传统疗法

乳腺癌是一个全球性的健康挑战,令人震惊的统计数据强调了其普遍影响。这种疾病的负担是根据其患病率及其对医疗保健系统构成的挑战来衡量的,因此有必要更仔细地研究其流行病学和影响。目前的乳腺癌治疗,包括手术、化疗、放射治疗和靶向治疗,在改善患者预后方面取得了重大进展。然而,它们并非没有局限性,常常导致不良反应和耐药性的产生。这篇全面的综述深入探讨了乳腺癌的复杂情况,包括其发病率、当前的治疗方式以及现有治疗方法的固有局限性。它还揭示了纳米技术在对抗乳腺癌中的前景光明的作用,其中包括无机和有机纳米颗粒,能够选择性地将治疗剂递送到肿瘤部位。该综述还讨论了新兴疗法、相关挑战以及乳腺癌治疗中靶向药物输送的未来前景。
更新日期:2024-04-10
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