Fascioliasis is a trematodiasis that affects domestic and wild animals as well as humans worldwide. It is a well-recognized disease in livestock, were it produces serious economic losses. Yet in cattle, there is limited information about the burden of liver flukes and its relation to the eggs per gram shed to the environment. There is also lack of knowledge on the effect of parasite load in blood parameters of infected animals, which is important to evaluate the severity and progression of the disease. The objective of this work was to gain insight in these aspects. Cattle from Mendoza province, Argentina, were inspected at a farm and at the abattoir determining the presence or absence of . Each animal was sampled for blood and feces and in the slaughterhouse the livers were inspected. Hematology and blood chemistry parameters were determined, feces were examined for eggs by a quantitative sedimentation technique and livers were thoroughly inspected to determine the number of flukes. Infected cattle presented a mild burden of liver flukes per animal, strongly correlated ( = 0.72) to the number of eggs per gram of feces. The total number of eggs (X̄=35,100) shed per animal to the environment and the type of livestock management techniques in the region exacerbate the role of cattle as efficient reservoirs of this disease. Statistically significant lower red blood cell, lymphocyte and neutrophil counts were observed in infected compared to uninfected animals. All hepatic parameters tested showed highly statistically significant differences ( < 0.001) as well as proteins by cause of rise of globulins in infected cattle. The correlation between the amount of flukes in the liver and the number of eggs per gram of faces indicates coprology as a reliable and cost-effective method to infer parasite burden. The impact of fascioliasis on blood parameters can be of aid for the veterinary practitioner on the assessment of this disease on cattle.

中文翻译：

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慢性片形吸虫病牛的血液参数和寄生虫负荷

片吸虫病是一种吸虫病，影响全世界的家畜和野生动物以及人类。这是一种众所周知的牲畜疾病，会造成严重的经济损失。然而，对于牛来说，关于肝吸虫的负担及其与每克排放到环境中的卵的关系的信息有限。人们还缺乏关于寄生虫负荷对受感染动物血液参数影响的了解，这对于评估疾病的严重程度和进展很重要。这项工作的目的是深入了解这些方面。来自阿根廷门多萨省的牛在农场和屠宰场接受了检查，以确定是否存在。对每只动物进行血液和粪便取样，并在屠宰场检查肝脏。测定血液学和血液化学参数，通过定量沉降技术检查粪便中的虫卵，并彻底检查肝脏以确定吸虫的数量。受感染的牛每只动物的肝吸虫负担较轻，与每克粪便中的虫卵数量密切相关（= 0.72）。每只动物向环境排放的鸡蛋总数（X̄=35,100）以及该地区牲畜管理技术的类型加剧了牛作为这种疾病的有效宿主的作用。与未感染的动物相比，感染动物的红细胞、淋巴细胞和中性粒细胞计数显着降低，具有统计学意义。所有测试的肝脏参数均显示出高度统计显着性差异（< 0.001），以及受感染牛球蛋白升高导致的蛋白质差异。肝脏中的吸虫数量与每克面部的虫卵数量之间的相关性表明粪便学是推断寄生虫负荷的可靠且经济有效的方法。片形吸虫病对血液参数的影响可以帮助兽医评估牛的这种疾病。