Constructing relatively inexpensive nanomaterials to simulate the catalytic performance of laccase is of great significance in recent years. Although research on improving laccase-like activity by regulating ligands of copper (amino acids or small organic molecules, etc.) have achieved remarkable success. There are few reports on improving laccase-like activity by adjusting the composition of metal Cu. Here, we used perovskite hydroxide AB(OH) as a model to evaluate the relationship between Cu based alloys and their laccase-like activity. We found that when the Cu/Mn alloy ratio of the perovskite hydroxide A point is greater than 1, the laccase-like activity of the binary alloy perovskite hydroxide is higher than that of the corresponding single Cu. Based on the measurements of XPS and ICP-MS, we deduced that the improvements of laccase-like activity mainly attribute to the ratio of Cu/Cuand the content of Cu. Moreover, two types of substrates (toxic pollutants and catechol neurotransmitters) were used to successfully demonstrated such nanozymes’ excellent environmental protecting function and biosensing property. This work will provide a novel approach for the construction and application of laccase-like nanozymes in the future.

中文翻译：

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具有可控活性的基于钙钛矿氢氧化物的漆酶模拟物，用于环境修复和生物传感

近年来构建相对廉价的纳米材料来模拟漆酶的催化性能具有重要意义。尽管通过调节铜的配体（氨基酸或有机小分子等）来提高漆酶样活性的研究已经取得了显着的成功。通过调整金属Cu的组成来提高类漆酶活性的报道较少。在这里，我们使用钙钛矿氢氧化物 AB(OH) 作为模型来评估铜基合金与其类漆酶活性之间的关系。我们发现，当钙钛矿氢氧化物A点的Cu/Mn合金比大于1时，二元合金钙钛矿氢氧化物的类漆酶活性高于相应的单一Cu。根据XPS和ICP-MS的测量，我们推断类漆酶活性的提高主要归因于Cu/Cu的比值和Cu的含量。此外，使用两种类型的底物（有​​毒污染物和儿茶酚神经递质）成功证明了此类纳米酶优异的环保功能和生物传感性能。该工作将为未来类漆酶纳米酶的构建和应用提供一种新的方法。