Providing insight into the mechanism of action of cationic lipidated oligomers using metabolomics,mSystems

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Providing insight into the mechanism of action of cationic lipidated oligomers using metabolomics
mSystems ( IF 6.4 ) Pub Date : 2024-04-12 , DOI: 10.1128/msystems.00093-24
Maytham Hussein _{1,

2} , Muhammad Bilal Hassan Mahboob ₃ , Jessica R. Tait ₃ , James L. Grace ₃ , Véronique Montembault ₄ , Laurent Fontaine ₄ , John F. Quinn _{3,

5} , Tony Velkov _{1,

2} , Michael R. Whittaker ₃ , Cornelia B. Landersdorfer ₃

Affiliation

Antimicrobial resistance poses a significant challenge to healthcare systems worldwide. Novel anti-infective therapeutics are urgently needed to combat drug-resistant microorganisms. Cationic lipidated oligomers (CLOs) show promise as new antibacterial ...

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