In the present research, novel lanthanide coordination compounds [DyL(PhCOO)(CH₃OH)](ClO₄)₂·(CH₃OH)₂ (1) were characterized by the compression of 2,6-diformyl-4-methyl-phenol (dmp) and 1,3-diamino-2-propanol using benzoate as the secondary ligand, where L indicates the deprotonated macrocyclic ligand. Through the high structural rigidity driven by the coordination of the macrocyclic ligand formed by condensation in methanol solution and sodium benzoate with Dy(ClO₄)₃·6H₂O, compound 1 exhibits outstanding cyan-emitting fluorescence performance and potential applications as a fluorescent material. Additionally, hyaluronic acid (HA)/ carboxymethyl chitosan (CMCS) hydrogels were prepared with loaded resveratrol metal-organic complexes according to the synthetic chemical approach. In biological study, we evaluated the effect of hydrogels on oxidative stress on human dermal fibroblasts. Examined by molecular docking simulation, the results showed that the binding interactions were from the phenol group, the carboxyl group and also the “-N=” group, indicating Dy metal complex has excellent biological capability.

本研究通过2,6-二甲酰基-4-甲基的压缩表征了新型镧系配位化合物[DyL(PhCOO)(CH ₃ OH)](ClO ₄ ) ₂ ·(CH ₃ OH) ₂ ( 1 ) -苯酚 (dmp) 和 1,3-二氨基-2-丙醇，使用苯甲酸酯作为第二配体，其中 L 表示去质子化的大环配体。通过在甲醇溶液和苯甲酸钠中缩合形成的大环配体与Dy(ClO ₄ ) ₃ ·6H ₂ O的配位驱动的高结构刚性，化合物1表现出优异的青色发射荧光性能和作为荧光材料的潜在应用。此外，根据合成化学方法，用负载白藜芦醇的金属有机配合物制备了透明质酸（HA）/羧甲基壳聚糖（CMCS）水凝胶。在生物学研究中，我们评估了水凝胶对人真皮成纤维细胞氧化应激的影响。分子对接模拟结果显示，结合相互作用来自酚基、羧基以及“-N=”基团，表明Dy金属配合物具有优异的生物学性能。