1,3,4‐Thiadiazole compounds were synthesized using pyridine carboxylic acid derivatives and thiosemicarbazide derivatives. The molecular structures of the resulting compounds were characterized by spectroscopic methods such as ATR‐FTIR, 1H‐NMR, and elemental analysis. Its compounds were also examined for their antibacterial properties against some strains of bacteria. Five synthesized compounds showed varying antibacterial effects on Escherichia coli, Salmonella kentucky, Bacillus substilis and Klebsiella pneumoniae. This result revealed that some of the resulting compounds could be antibacterial agents.

中文翻译：

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具有吡啶部分的新型抗菌 1,3,4-噻二唑衍生物

使用吡啶羧酸衍生物和氨基硫脲衍生物合成1,3,4-噻二唑化合物。通过 ATR-FTIR、1H-NMR 和元素分析等光谱方法对所得化合物的分子结构进行了表征。还检查了其化合物对某些细菌菌株的抗菌特性。五种合成的化合物对大肠杆菌、肯塔基沙门氏菌、枯草芽孢杆菌和肺炎克雷伯菌表现出不同的抗菌作用。这一结果表明，一些所得化合物可能是抗菌剂。