当前位置: X-MOL 学术Int. J. Biol. Macromol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Effect of ultrasonic power on delivery of quercetin in emulsions stabilized using octenyl succinic anhydride (OSA) modified broken japonica rice starch
International Journal of Biological Macromolecules ( IF 8.2 ) Pub Date : 2024-04-14 , DOI: 10.1016/j.ijbiomac.2024.131557
Xue Wang , Ning Wang , Dandan Wu , Liqi Wang , Na Zhang , Dianyu Yu

In this study, emulsions stabilized by octenyl succinic anhydride-modified broken japonica rice starch (OSA-BJRS) were prepared at different ultrasonic power intensities for the delivery, controlled release, and improved bioavailability of quercetin. The OSA-BJRS emulsions ultrasonicated at 400 W exhibited the highest encapsulation efficiency (89.37 %) and loading efficiency (58.34 %) of quercetin, the smallest volume-average droplet diameter (0.51 μm) and polydispersity index (0.19), the highest absolute value of the ζ-potential (26.73 mV), and the highest apparent viscosity and viscoelasticity. The oxidation stability, storage stability, thermal stability, and salt ion stability of the emulsions were also notably improved by the ultrasonication treatment. In addition, the results of the simulated digestion demonstrated that the ultrasonicated OSA-BJRS emulsions had an enhanced quercetin delivery performance and could stably transport quercetin to the small intestine for digestion. The OSA-BJRS emulsion ultrasonicated at 400 W exhibited the highest cumulative release rate (95.91 %) and the highest bioavailability (30.48 %) of quercetin. This suggests that OSA-BJRS emulsions prepared by ultrasonication can be considered effective delivery systems for hydrophobic functional components.

中文翻译:

超声功率对辛烯基琥珀酸酐 (OSA) 改性破碎粳米淀粉稳定乳液中槲皮素传递的影响

在本研究中,在不同的超声功率强度下制备了由辛烯基琥珀酸酐改性的碎粳米淀粉(OSA-BJRS)稳定的乳液,以递送、控制释放并提高槲皮素的生物利用度。 400 W超声处理的OSA-BJRS乳液表现出最高的槲皮素包封率(89.37 %)和负载率(58.34 %),最小的体积平均液滴直径(0.51 μm)和多分散指数(0.19),绝对值最高的 z 电位 (26.73 mV),以及最高的表观粘度和粘弹性。超声处理也显着提高了乳液的氧化稳定性、储存稳定性、热稳定性和盐离子稳定性。此外,模拟消化的结果表明,超声处理的OSA-BJRS乳液具有增强的槲皮素递送性能,并且可以稳定地将槲皮素转运至小肠进行消化。 400 W超声处理的OSA-BJRS乳液表现出最高的槲皮素累积释放率(95.91%)和最高的生物利用度(30.48%)。这表明超声处理制备的 OSA-BJRS 乳液可以被认为是疏水性功能成分的有效递送系统。
更新日期:2024-04-14
down
wechat
bug