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SARS-CoV-2 IgG Levels as Predictors of XBB Variant Neutralization, Israel, 2022­ and 2023
Emerging Infectious Diseases ( IF 11.8 ) Pub Date : 2024-04-16 , DOI: 10.3201/eid3005.231739
Yaniv Lustig , Michal Canetti , Victoria Indenbaum , Yovel Peretz , Yael Weiss-Ottolenghi , Ili Margalit , Keren Asraf , Tal Levin , Neta Zuckerman , Enosh Tomer , Michal Mandelboim , Ram Doolman , Noam Barda , Gili Regev-Yochay

Although a vaccine against SARS-CoV-2 Omicron-XBB.1.5 variant is available worldwide and recent infection is protective, the lack of recorded infection data highlights the need to assess variant-specific antibody neutralization levels. We analyzed IgG levels against receptor-binding domain–specific SARS-CoV-2 ancestral strain as a correlate for high neutralizing titers against XBB variants.



中文翻译:

SARS-CoV-2 IgG 水平作为 XBB 变异中和的预测因子,以色列,2022 年和 2023 年

尽管针对 SARS-CoV-2 Omicron-XBB.1.5 变体的疫苗在全球范围内可用,并且最近的感染具有保护性,但缺乏记录的感染数据凸显了评估变体特异性抗体中和水平的必要性。我们分析了针对受体结合域特异性 SARS-CoV-2 祖先毒株的 IgG 水平,将其作为针对 XBB 变体的高中和滴度的相关性。

更新日期:2024-04-17
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