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Comparison of Non-ephedrine Constituents from Ephedra Plants Cultivated in Japan
Chemical & Pharmaceutical Bulletin ( IF 1.7 ) Pub Date : 2024-04-17 , DOI: 10.1248/cpb.c24-00043
Kengo Hayashi 1 , Yuki Miyao 1 , Hina Matsui 1 , Takao Yamaura 2 , Ken Tanaka 1 , Mariko Baba 1 , Hiroaki Hayashi 1
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Ephedra plants, the main components of which are ephedrine alkaloids, are used as traditional medicines in Eastern Asian countries. In this study, we isolated non-ephedrine constituents from various Ephedra plant species cultivated in Japan. HPLC analysis suggested that kynurenic acid and its derivatives accumulated in a wide range of Ephedra plant species. Furthermore, a large amount of (2R,3S)-O-benzoyl isocitrate has been isolated from E. intermedia. This study suggests that Ephedra plants have diverse non-ephedrine constituents.

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中文翻译:

日本栽培的麻黄植物的非麻黄碱成分比较

麻黄植物的主要成分是麻黄碱,在东亚国家被用作传统药物。在这项研究中,我们从日本种植的各种麻黄植物中分离出了非麻黄碱成分。 HPLC 分析表明犬尿酸及其衍生物在多种麻黄植物中积累。此外,还从E. intermedia中分离出大量的(2R , 3S ) -O-苯甲酰基异柠檬酸酯。这项研究表明麻黄植物具有多种非麻黄碱成分。

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更新日期:2024-04-18
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