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Uptake and 4-week quit rates from an opt-out co-located smoking cessation service delivered alongside community-based low-dose computed tomography screening within the Yorkshire Lung Screening Trial
European Respiratory Journal ( IF 24.3 ) Pub Date : 2024-04-18 , DOI: 10.1183/13993003.01768-2023
Rachael L. Murray , Panos Alexandris , David Baldwin , Kate Brain , John Britton , Philip A.J. Crosbie , Rhian Gabe , Sarah Lewis , Steve Parrott , Samantha L. Quaife , Hui Zhen Tam , Qi Wu , Rebecca Beeken , Harriet Copeland , Claire Eckert , Neil Hancock , Jason Lindop , Grace McCutchan , Catriona Marshall , Richard D. Neal , Suzanne Rogerson , Harriet D. Quinn Scoggins , Irene Simmonds , Rebecca Thorley , Matthew E. Callister

Extract

Low-dose computed tomography (LDCT) screening for lung cancer has been shown to reduce lung cancer-specific mortality in two large, randomised trials [1, 2], and implementation of screening is currently underway in many high- and middle-income countries [3]. Of those people responding to an invitation for lung cancer screening and subsequently eligible, between 30% and 50% are currently smoking [4, 5]. Evidence of the impact of screening alone on smoking cessation rates in randomised trials is mixed. Three studies have compared quit rates in participants randomised to LDCT screening versus a non-screened control group, with one study showing an increased quit rate in the screened group [6], one study showing no difference between screened and non-screened participants [7], and one study showing a higher quit rate in non-screened participants, although this effect did not persist after intention-to-treat analysis [8]. Importantly, smoking cessation interventions were minimal in all three studies, comprising signposting to existing services, written information to support quit attempts and (in one study) very brief advice [6–8].



中文翻译:

在约克郡肺部筛查试验中,与基于社区的低剂量计算机断层扫描筛查一起提供的选择退出同地戒烟服务的接受率和 4 周戒烟率

提炼

两项大型随机试验显示,低剂量计算机断层扫描 (LDCT) 筛查肺癌可降低肺癌特异性死亡率 [1, 2],许多高收入和中等收入国家目前正在实施筛查[3]。在那些响应肺癌筛查邀请并随后符合资格的人中,30% 到 50% 目前正在吸烟 [4, 5]。随机试验中单独筛查对戒烟率影响的证据好坏参半。三项研究比较了随机接受 LDCT 筛查的参与者未筛查对照组的戒烟率,其中一项研究显示筛查组的戒烟率有所增加 [6],一项研究显示筛查组和未筛查参与者之间没有差异 [7 ],一项研究显示,未经筛选的参与者的戒烟率较高,尽管这种效应在意向治疗分析后并未持续存在[8]。重要的是,所有三项研究中的戒烟干预措施都很少,包括现有服务的路标、支持戒烟尝试的书面信息以及(在一项研究中)非常简短的建议[6-8]。

更新日期:2024-04-18
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