Mining the potential of traditional Chinese medicine (TCM) in treating modern diseases requires a profound understanding of its action mechanism and a comprehensive knowledge system that seamlessly bridges modern medical insights with traditional theories. However, existing databases for modernizing TCM are plagued by varying degrees of information loss, which impede the multidimensional dissection of pharmacological effects. To address this challenge, we introduce traditional Chinese medicine modernization (TCMM), the currently largest modernized TCM database that integrates pioneering intelligent pipelines. By aligning high-quality TCM and modern medicine data, TCMM boasts the most extensive TCM modernization knowledge, including 20 types of modernized TCM concepts such as prescription, ingredient, target and 46 biological relations among them, totaling 3,447,023 records. We demonstrate the efficacy and reliability of TCMM with two features, prescription generation and knowledge discovery, the outcomes show consistency with biological experimental results. A publicly available web interface is at .

中文翻译：

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TCMM：中药现代化和治疗创新的统一数据库

挖掘中医药治疗现代疾病的潜力，需要对其作用机制的深刻理解，以及将现代医学见解与传统理论无缝衔接的全面知识体系。然而，现有的中医药现代化数据库都存在不同程度的信息丢失问题，这阻碍了药理作用的多维剖析。为了应对这一挑战，我们引入了传统中药现代化（TCMM），这是目前最大的集成了先进智能管道的现代化中药数据库。通过对接高质量的中医和现代医学数据，TCMM拥有最广泛的中医现代化知识，包括方剂、成分、靶标等20种现代化中医概念及其之间的46个生物学关系，总计3,447,023条记录。我们通过处方生成和知识发现两个特征证明了 TCMM 的有效性和可靠性，结果与生物学实验结果一致。公开可用的 Web 界面位于 。