In patients with aortic dissection, the aortic wall is separated into two layers along a dissection plane. In this study, a survey was performed to investigate the distribution of the depth of dissection plane and its correlation with other clinical and pathological parameters to help understand and expand the current knowledge of aortic dissection. Pathology information system were searched for patients with aortic dissection who had undergone aortic replacement between 2019 and 2022 in Wuhan Asia General Hospital. The depth of dissection plane and dissection depth index were measured in the area around the edge of dissection plane. Correlation between parameters was calculated using Spearman's rank correlation coefficient. 124 patients were included in this study. The depth of dissection plane ranged from 533 to 2335 microns, and the 5th percentile was 778 microns. The dissection depth index ranged from 0.320 to 0.972, and the 5th percentile was 0.503. The correlation coefficients were -0.305 (=.0007), -0.259 (=0.0111), 0.188 (=0.0367), 0.189 (=0.0359) respectively for male gender, the length of aortic dissection, atherosclerosis, and translamellar mucoid extracellular matrix accumulation. In 95% of patients with aortic dissection, the depth of dissection plane is larger than 778 microns, and the dissection depth index is greater than 0.503. In other words, aortic dissection rarely occurs in the inner 50.3% of the aortic media. The dissection depth index is negatively correlated with male gender and the length of aortic dissection, and positively correlated with atherosclerosis and translamellar mucoid extracellular matrix accumulation.

中文翻译：

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主动脉夹层深度分布及夹层深度指数与其他参数的相关性

在主动脉夹层患者中，主动脉壁沿夹层平面分为两层。在本研究中，进行了一项调查来调查夹层平面深度的分布及其与其他临床和病理参数的相关性，以帮助理解和扩展当前对主动脉夹层的认识。检索病理信息系统中2019年至2022年在武汉亚洲总医院接受主动脉置换术的主动脉夹层患者。在解剖平面边缘周围的区域测量解剖平面深度和解剖深度指数。使用斯皮尔曼等级相关系数计算参数之间的相关性。本研究纳入了 124 名患者。解剖平面深度范围为 533 至 2335 微米，第 5 个百分位数为 778 微米。解剖深度指数范围为0.320至0.972，第5个百分位数为0.503。男性、主动脉夹层长度、动脉粥样硬化和跨层粘液细胞外基质积聚的相关系数分别为-0.305（=.0007）、-0.259（=0.0111）、0.188（=0.0367）、0.189（=0.0359）。 95%的主动脉夹层患者夹层平面深度大于778微米，夹层深度指数大于0.503。也就是说，主动脉夹层很少发生在主动脉中层内侧50.3%的区域。夹层深度指数与男性性别、主动脉夹层长度呈负相关，与动脉粥样硬化、跨层粘液细胞外基质积聚呈正相关。