Skin-interfaced microfluidic patch has become a reliable device for sweat collection and analysis. However, the intractable problems of emptying the microchannel for reuse, and the channel's volumetric capacity limited by the size of the patch, directly hinder the practical application of sweat sensors. Herein, we report an adaptively resettable microfluidic sweat patch (Art-Sweat patch) capable of continuously monitoring both sweat rate (0.2–4.0 μL min) and total ionic charge concentration (10–200 mmol L). We develop a platform with a vertical and horizontal microchannel combined strategy, enabling repeatedly filling sweat and emptying the microchannel for autonomously resetting and detecting. The variation in the emptied volume is designed to be adaptively identified by the sensor, resulting in enhanced stability and an enlarged volumetric capacity of over 300 μL. By integrating with self-designed wireless transmission modules, the proposed Art-Sweat patch shows product-level wearability and high performance in monitoring variations in regional sweat rate and concentration for hydration status assessment.

中文翻译：

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用于出汗率和电解质检测的自适应可重置微流体贴片

皮肤界面微流体贴片已成为汗液收集和分析的可靠设备。然而，清空微通道以供重复使用的棘手问题以及通道容量受贴片尺寸限制，直接阻碍了汗液传感器的实际应用。在此，我们报告了一种自适应可重置微流体汗贴（Art-Sweat贴片），能够连续监测出汗率（0.2-4.0μL/min）和总离子电荷浓度（10-200mmol·L）。我们开发了一个具有垂直和水平微通道组合策略的平台，能够反复填充汗液和排空微通道以进行自主重置和检测。排空体积的变化旨在由传感器自适应识别，从而增强稳定性并将体积容量扩大到超过 300 μL。通过与自行设计的无线传输模块集成，所提出的Art-Sweat贴片在监测区域出汗率和浓度变化以评估水合状态方面表现出产品级的耐磨性和高性能。