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Synthesis and characterization of biocompatible multifunctional potassium ferrite nanoparticles for its varied applications
Applied Physics A ( IF 2.7 ) Pub Date : 2024-04-18 , DOI: 10.1007/s00339-024-07456-0
Md Muzzammilul Haque Siddiqui , Md Irfanul Haque Siddiqui , Md. Masood Rashid , Nishant Kumar

The current study reports on the shape, size distribution, structure, magnetic properties, and biocompatibility of potassium ferrite nanoparticles (KFeO2 NPs), which were produced using the traditional sol–gel method. The development of spherical nanoparticles with an orthorhombic structure has been verified using X-ray diffraction and Field emission scanning electron microscopy. According to transmission electron microscopy, the particles have a size of about 30 nm. The production of metal (Fe, K) bonds was demonstrated by thermogravimetric analysis and Fourier transform-infrared spectroscopy. The optical analysis shows that the KFeO2 nanoparticles' bandgap is 1.88 eV, which is within the visible spectrum. Further Photoluminescent properties were investigated and showed strong luminescence in 600 nm range thus confirming oxygen deficient property. The synthesized KFeO2 NPs exhibited superparamagnetic behavior, with a saturation magnetization of 22.12 emu/g, according to the vibrating sample magnetometer examination. Furthermore, as determined by MTT and BrdU assays, the observed in vitro cytotoxicity and lymphoproliferative effects appeared to be biocompatible and concentration-dependent. The MTT assay was used in an in vitro cytotoxicity test which demonstrated the biocompatibility of KFeO2 NPs at 100 mg/mL of particle concentration. The findings of the current study suggest that potassium ferrite magnetic nanomaterials, which have better optical qualities and less coercivity in optoelectronic instruments, could be used in transformer cores. They can also be used as iron-oxide-based nanomaterials for applications in the health and medical science sectors.



中文翻译:

生物相容性多功能铁酸钾纳米粒子的合成和表征及其各种应用

目前的研究报告了使用传统溶胶-凝胶方法生产的铁酸钾纳米粒子(KFeO 2 NPs)的形状、尺寸分布、结构、磁性和生物相容性。使用X射线衍射和场发射扫描电子显微镜验证了具有斜方结构的球形纳米粒子的发展。根据透射电子显微镜,颗粒的尺寸约为30 nm。通过热重分析和傅里叶变换红外光谱证明了金属(Fe,K)键的产生。光学分析表明KFeO 2纳米粒子的带隙为1.88 eV,位于可见光谱范围内。研究了进一步的光致发光特性,并在 600 nm 范围内显示出强发光,从而证实了缺氧特性。根据振动样品磁力计检测,合成的KFeO 2 NPs表现出超顺磁行为,饱和磁化强度为22.12 emu/g。此外,通过 MTT 和 BrdU 测定确定,观察到的体外细胞毒性和淋巴增殖效应似乎具有生物相容性和浓度依赖性。 MTT法用于体外细胞毒性测试,证明了KFeO 2 NPs在100 mg/mL颗粒浓度下的生物相容性。目前的研究结果表明,钾铁氧体磁性纳米材料在光电仪器中具有更好的光学质量和更低的矫顽力,可用于变压器铁芯。它们还可以用作氧化铁基纳米材料,用于健康和医学科学领域。

更新日期:2024-04-19
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