Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs), as two typical porous topological materials with large specific surface area, high porosity, and abundant structural synthesis and modification methods, have been widely implemented in the fields of adsorption, catalysis, biomedicine, and sensing. This review starts with an overview of the features, types, history, synthesis techniques of MOFs and COFs and their functionalization of target properties. Then it illustrates the advantages of MOFs and COFs in electrochemical, optical and other sensing methods for biological and chemical analysis. More importantly, this review highlights the recent advances of MOFs/COFs-based sensing devices in healthcare and environmental fields including wearable and flexible, microfluidic, and hydrogel sensing devices. Finally, the challenges and prospects for the application of MOFs/COFs in integrated sensing devices are discussed. It is beneficial for researchers to further design and develop novel MOFs/COFs-based integrated and miniaturized sensing devices for point-of-care testing and risk monitoring applications.

中文翻译：

---

基于金属有机框架 (MOF) 和共价有机框架 (COF) 的集成传感设备原型设计，用于稳健分析

金属有机骨架材料（MOFs）和共价有机骨架材料（COFs）作为两种典型的多孔拓扑材料，具有比表面积大、孔隙率高、结构合成和改性方法丰富等优点，已广泛应用于吸附、催化、生物医学和传感。本综述首先概述了 MOF 和 COF 的特征、类型、历史、合成技术及其目标特性的功能化。然后阐述了MOF和COF在电化学、光学和其他生物和化学分析传感方法中的优势。更重要的是，这篇综述强调了基于 MOF/COF 的传感设备在医疗保健和环境领域的最新进展，包括可穿戴和柔性、微流体和水凝胶传感设备。最后，讨论了MOF/COF在集成传感器件中应用的挑战和前景。这有利于研究人员进一步设计和开发基于 MOF/COF 的新型集成和小型化传感设备，用于即时测试和风险监测应用。