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The Effect of Coenzyme Q10 Supplementation on Bile Acid Metabolism: Insights from Network Pharmacology, Molecular Docking, and Experimental Validation
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2024-04-21 , DOI: 10.1002/mnfr.202400147
Mengcheng Jin 1 , Tangbin Zou 2 , Hairong Huang 3 , Ming Chen 1 , Haoqi Zou 1 , Baoyan Chen 1 , Chengze Lai 1 , Huawen Li 1 , Peiwen Zhang 1
Affiliation  

Bile acids play a crucial role in lipid absorption and the regulation of lipid, glucose, and energy homeostasis. Coenzyme Q10 (CoQ10), a lipophilic antioxidant, has been recognized for its positive effects on obesity and related glycolipid metabolic disorders. However, the relationship between CoQ10 and bile acids has not yet been evaluated.

中文翻译:

补充辅酶 Q10 对胆汁酸代谢的影响:来自网络药理学、分子对接和实验验证的见解

胆汁酸在脂质吸收以及脂质、葡萄糖和能量稳态的调节中起着至关重要的作用。辅酶 Q10 (CoQ10) 是一种亲脂性抗氧化剂,因其对肥胖和相关糖脂代谢紊乱的积极作用而得到认可。然而,CoQ10 和胆汁酸之间的关系尚未得到评估。
更新日期:2024-04-21
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