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Synthesis, characterization, and biological evaluation of novel cinnamic acid derivatives: cinnamoyl-metronidazole ester and cinnamoyl-memantine amide
Heliyon ( IF 4 ) Pub Date : 2024-04-21 , DOI: 10.1016/j.heliyon.2024.e29851
Mohammad Moatz Shollar , Joumaa Merzaa , Maher Darwish , Mohammad Keshe

In this study, two derivatives, namely the ester derivative cinnamoyl metronidazole and the amide derivative cinnamoyl memantine, were synthesized from cinnamic acid and respective drugs for the purpose of exploring their potential as novel and efficient antimicrobial agents in the quest of prevailing the global antimicrobial resistance challenge.

中文翻译:

新型肉桂酸衍生物:肉桂酰甲硝唑酯和肉桂酰美金刚酰胺的合成、表征和生物学评价

在本研究中,由肉桂酸和相应药物合成了两种衍生物,即酯衍生物肉桂酰甲硝唑和酰胺衍生物肉桂酰美金刚,旨在探索它们作为新型高效抗菌药物的潜力,以应对全球抗菌药物耐药性。挑战。
更新日期:2024-04-21
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